Product Name	Anti-Jaw1/PE
Chinese Name	PE标记的淋巴限制膜蛋白Jaw1抗体
Alias	Lrmp; LRMP_HUMAN; Lymphoid restricted membrane protein; Lymphoid restricted membrane protein; Processed lymphoid-restricted membrane protein; Protein Jaw1.
Research Area	Cell biology  Signal transduction  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	62kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Jaw1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encode dby this gene is expressed in a developmentally regulated manner in lymphoid cell lines and tissues. The protein is localized to the cytoplasmic face of the endoplasmic reticulum. [provided by RefSeq, Jul 2008] Function: Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion. Subunit: Interacts (via coiled-coil domain) with ITPR3. Subcellular Location: Cytoplasm and Endoplasmic reticulum membrane. Tissue Specificity: Expressed at high levels in pre B-cells, mature B-cells and pre T-cells. Expressed at low levels in mature T-cells and plasma B-cells. Post-translational modifications: The removal of the C-terminal lumenal domain occurs by proteolytic processing. Database links: Entrez Gene: 4033 Human Omim: 602003 Human SwissProt: Q12912 Human Unigene: 124922 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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