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Product Name Anti-KIAA1486/PE Chinese Name PE标记的KIAA1486蛋白抗体 Alias K1486_HUMAN; KIAA1486; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2; NYAP2; Uncharacterized protein KIAA1486. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 71kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human KIAA1486 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
Activates PI3K and concomitantly recruits the WAVE1Ccomplex to the close vicinity of PI3K and regulates neuronal morphogenesis.
Subunit:
Interacts with ACOT9, ARHGAP26 and PIK3R2. Interacts with components of the WAVE1 complex, CYFIP1 and NCKAP1; this interaction mediates PI3K-WAVE1 association and actin cytoskeleton remodeling
Post-translational modifications:
Phosphorylated on tyrosine residues by FYN upon stimulation with CNTN5.
Similarity:
Belongs to the NYAP family.
Database links:Entrez Gene: 57624 Human
SwissProt: Q9P242 Human
Unigene: 224409 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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