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Rabbit Anti-Jaw1/PE-Cy3 Conjugated antibody
Rabbit Anti-Jaw1/PE-Cy3 Conjugated antibody
Lrmp; LRMP_HUMAN; Lymphoid restricted membrane protein; Lymphoid restricted membrane protein; Processed lymphoid-restricted membrane protein; Protein Jaw1.
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Details

Product Name Anti-Jaw1/PE-Cy3
Chinese Name PE-Cy3标记的淋巴限制膜蛋白Jaw1抗体
Alias Lrmp; LRMP_HUMAN; Lymphoid restricted membrane protein; Lymphoid restricted membrane protein; Processed lymphoid-restricted membrane protein; Protein Jaw1.  
Research Area Cell biology  Signal transduction  The cell membrane蛋白  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Rat,  (predicted: Mouse, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 62kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Jaw1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encode dby this gene is expressed in a developmentally regulated manner in lymphoid cell lines and tissues. The protein is localized to the cytoplasmic face of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]

Function:
Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion.

Subunit:
Interacts (via coiled-coil domain) with ITPR3.

Subcellular Location:
Cytoplasm and Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed at high levels in pre B-cells, mature B-cells and pre T-cells. Expressed at low levels in mature T-cells and plasma B-cells.

Post-translational modifications:
The removal of the C-terminal lumenal domain occurs by proteolytic processing.

Database links:

Entrez Gene: 4033 Human

Omim: 602003 Human

SwissProt: Q12912 Human

Unigene: 124922 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Partial purchase records(bought amounts latest4)

UsernameQuantitybought time
Um***22024-06-17
Ow***12024-03-30
Ra***12024-01-06
Ka***22023-08-16
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