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Product Name Anti-C3orf23/Cy5.5 Chinese Name Cy5.5标记的3号染色体开放阅读框23抗体 Alias C3orf23; CC023_HUMAN; Chromosome 3 open reading frame 23; D9Ertd402e; Hypothetical protein LOC285343; TOAG1; Tolerance associated gene 1; Uncharacterized protein C3orf23. Research Area Tumour Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 58kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human C3orf23 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
C3orf23, also known as FLJ41686, MGC119530, MGC119531, MGC119532, MGC119533 or DKFZp313N062, is a 496 amino acid protein that exists as four alternatively spliced isoforms. C3orf23 is encoded by a gene mapping to human chromosome 3p21.33. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Function:
May regulate T-cell apoptosis (By similarity).
Subcellular Location:
Mitochondrion (By similarity).
Database links:Entrez Gene: 285343 Human
SwissProt: Q8N3R3 Human
SwissProt: Q66JZ4 Mouse
Unigene: 55131 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Username | Quantity | bought time |
Fi*** | 1 | 2023-06-18 |
So*** | 2 | 2023-06-17 |
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