Product Name	Anti-CD161c/APC
Chinese Name	APC标记的CD161c抗体
Alias	CD161 antigen like family member C; CD161 antigen-like family member C; CD161c; Killer cell lectin like receptor subfamily A member 1C; Killer cell lectin like receptor subfamily B member 1C; Klrb1c; Ly55c; Lymphocyte antigen 55c; Ly59; Lymphocyte antigen 59; Natural killer cell surface protein P1 40; Natural killer cell surface protein P1-40; Ly-55c; NK1.1 alloantigen; NKR P1.9; NKR P1C; NKRP1 40; NKRP1; NKRP1.9; Nkrp1-c; NKRP1C; NK-1.1; Nk-1.2; NK-RP1; NK1.1; NKR-P1; Nkrp1c; NKR-P1.9; NKR-P1C; KLRB1_MOUSE.
Research Area	Tumour  Signal transduction  The cell membrane受体  Natural killer cells  t-lymphocyte  epithelial cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	25kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from mouse CD161/NK1.1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: NK1.1, a member of the NKRPI family of cell surface receptors, is a type II integral membrane protein with a C type lectin domain. It is expressed as a disulfide linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57/BL6, FVB/N, NZB; but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, SJL, 129). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. Subunit: Homodimer; disulfide-linked. Interacts with acid phingomyelinase/SMPD1. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Tissue Specificity: Expressed in a subset of NK cells predominantly in intestinal epithelium and liver. Detected in peripheral blood T-cells and preferentially in adult T-cells with a memory antigenic phenotype. Similarity: Contains 1 C-type lectin domain. Database links: Entrez Gene: 3820 Human Entrez Gene: 100043861 Mouse Entrez Gene: 362443 Rat Omim: 602890 Human SwissProt: Q12918 Human SwissProt: Q0ZUP1 Mouse SwissProt: Q0ZUP0 Rat Unigene: 169824 Human Unigene: 66911 Mouse Unigene: 198693 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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