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Rabbit Anti-GDPD5/APC Conjugated antibody
Rabbit Anti-GDPD5/APC Conjugated antibody
GDE2; Gdpd5; GDPD5_HUMAN; Glycerophosphodiester phosphodiesterase 2; Glycerophosphodiester phosphodiesterase domain containing 5; Glycerophosphodiester phosphodiesterase domain-containing protein 5; PP1665.
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  • NO.:SL9207R-APC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,)
    Applications:ICC IF
    concentration:1mg/ml
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Details

Product Name Anti-GDPD5/APC
Chinese Name APC标记的甘油磷酸二酯酶磷酸结构域5抗体
Alias GDE2; Gdpd5; GDPD5_HUMAN; Glycerophosphodiester phosphodiesterase 2; Glycerophosphodiester phosphodiesterase domain containing 5; Glycerophosphodiester phosphodiesterase domain-containing protein 5; PP1665.  
Research Area Cell biology  immunology  Neurobiology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 69kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GDPD5
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.

Function:
Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.

Subunit:
Interacts with PRDX1; forms a mixed-disulfide with PRDX1, leading to disrupt intramolecular disulfide bond between Cys-25 and Cys-571 (By similarity).

Subcellular Location:
Endomembrane system. Cytoplasm; perinuclear region. Cell projection; growth cone. In a punctate perinuclear pattern.

Post-translational modifications:
Intramolecular disulfide bond between Cys-25 and Cys-571 is reduced by PRDX1 (By similarity).

Similarity:
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Contains 1 GDPD domain.

Database links:

Entrez Gene: 81544 Human

Entrez Gene: 233552 Mouse

Entrez Gene: 100627912 Pig

Entrez Gene: 499211 Rat

Omim: 609632 Human

SwissProt: Q8WTR4 Human

SwissProt: Q640M6 Mouse

Unigene: 503297 Human

Unigene: 286317 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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