Product Name	Anti-C3orf23/APC
Chinese Name	APC标记的3号染色体开放阅读框23抗体
Alias	C3orf23; CC023_HUMAN; Chromosome 3 open reading frame 23; D9Ertd402e; Hypothetical protein LOC285343; TOAG1; Tolerance associated gene 1; Uncharacterized protein C3orf23.
Research Area	Tumour  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	58kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human C3orf23
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: C3orf23, also known as FLJ41686, MGC119530, MGC119531, MGC119532, MGC119533 or DKFZp313N062, is a 496 amino acid protein that exists as four alternatively spliced isoforms. C3orf23 is encoded by a gene mapping to human chromosome 3p21.33. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3. Function: May regulate T-cell apoptosis (By similarity). Subcellular Location: Mitochondrion (By similarity). Database links: Entrez Gene: 285343 Human SwissProt: Q8N3R3 Human SwissProt: Q66JZ4 Mouse Unigene: 55131 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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