Product Name	Anti-GlyR alpha 1 + 2 + 3/AF594
Chinese Name	AF594标记的甘氨酸受体alpha 1/2/3型抗体
Alias	glycine receptor alpha 1; glycine receptor alpha 2; glycine receptor alpha 3; GLRA1; GLRA2; Glycine receptor 48 kDa subunit; Glycine receptor alpha 2; Glycine receptor subunit alpha 3; Glycine receptor subunit alpha 2; Glycine receptor, alpha 1 subunit; Glycine receptor, alpha 2 subunit; MGC138878; MGC138879; STHE; alpha 1 Glycine Receptor; GLRA1; GLRA1_HUMAN; Glycine receptor 48 kDa subunit; Glycine receptor alpha 1; Glycine receptor strychnine-binding subunit; Glycine receptor subunit alpha-1; Glycine receptor, alpha 1 subunit; HKPX1; STHE; GLR; Glra2; GLRA2_HUMAN; Glycine receptor alpha 2 polypeptide; Glycine receptor alpha 2 subunit; Glycine receptor subunit alpha 2; Glycine receptor subunit alpha-2; Gycine receptor alpha 2.
Research Area	immunology  Neurobiology  Channel protein  The cell membrane受体  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	49kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GlyR alpha 1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Glycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation. Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain. Subcellular Location: Cell Membrane Database links: Entrez Gene: 2741 Human Entrez Gene: 14654 Mouse Entrez Gene: 25674 Rat Entrez Gene: 281783 Cow Entrez Gene: 489172 Dog Omim: 138491 Human SwissProt: P57695 Cow SwissProt: P23415 Human SwissProt: Q64018 Mouse SwissProt: P07727 Rat Unigene: 121490 Human Unigene: 89320 Mouse Unigene: 10109 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 甘氨酸受体alpha 1是中枢神经系统中的重要抑制性离子通道受体，是哺乳类中枢神经系统中神经递质受体蛋白，属于配体门控离子通道超家族成员.

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