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Rabbit Anti-CNGA2/AF594 Conjugated antibody
Rabbit Anti-CNGA2/AF594 Conjugated antibody
CNGA2; CNCA; CNCA1; CNG2; FLJ46312; OCNC1; OCNCa;OCNCALPHA; olfactory cyclic nucleotide-gated ion channel alpha subunit; olfactory ion channel protein; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-
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Product Name Anti-CNGA2/AF594
Chinese Name AF594标记的环核苷酸阳离子Channel proteinα2抗体
Alias CNGA2; CNCA; CNCA1; CNG2; FLJ46312; OCNC1; OCNCa;OCNCALPHA; olfactory cyclic nucleotide-gated ion channel alpha subunit; olfactory ion channel protein; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated channel alpha-2; CNG channel alpha-2; CNG-2; Cyclic nucleotide-gated olfactory channel subunit OCNC1; CNGA2_HUMAN.  
Research Area Cardiovascular  Neurobiology  Channel protein  
Immunogen Species Rabbit
Clonality Polyclonal
React Species
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 73kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CNGA2 (155-250aa)
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. CNGA2 belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family and contains one cyclic nucleotide-binding domain. It may be involved in odorant signal transduction. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.

Function:
Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily.
Contains 1 cyclic nucleotide-binding domain.

Database links:

Entrez Gene: 1260 Human

Entrez Gene: 12789 Mouse

Entrez Gene: 25411 Rat

Omim: 300338 Human

SwissProt: Q16280 Human

SwissProt: Q62398 Mouse

SwissProt: Q00195 Rat

Unigene: 447360 Human

Unigene: 5097 Mouse

Unigene: 10384 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

环核苷酸阳离子Channel proteinα2为阳离子通道结构蛋白。

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UsernameQuantitybought time
Da***12024-07-16
Os***22024-03-11
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