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Product Name Anti-COX7A2/AF488 Chinese Name AF488标记的细胞色素C氧化酶蛋白7A2抗体 Alias COX7A2; COX7AL; COX7AL1; COXVIIa L; COXVIIAL; CX7A2_HUMAN; Cytochrome c oxidase polypeptide 7A2 mitochondrial; Cytochrome c oxidase polypeptide VIIa liver/heart; Cytochrome c oxidase subunit 7A2; Cytochrome c oxidase subunit 7A2 mitochondrial; Cytochrome c oxidase subunit VIIa polypeptide 2; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit VIIa-liver/heart; Cytochrome c oxidase subunit VIIaL; Hepatic cytochrome c oxidase chain VIIa; MGC118950; MGC118951; MGC118952; MGC126875; MGC126877; mitochondrial; VIIAL. Research Area Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 6.7kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human COX7A2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]
Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular Location:
Mitochondrion inner membrane.
Similarity:
Belongs to the cytochrome c oxidase VIIa family.
Database links:Omim: 123996 Human
SwissProt: P14406 Human
SwissProt: P48771 Mouse
Unigene: 70312 Human
Unigene: 152627 Mouse
Unigene: 1745 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Username | Quantity | bought time |
Na*** | 1 | 2024-07-26 |
Ha*** | 1 | 2024-06-28 |
Be*** | 2 | 2024-04-21 |
Iv*** | 2 | 2024-03-13 |
Da*** | 2 | 2024-01-18 |
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