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Rabbit Anti-PNMT/AF350 Conjugated antibody
Rabbit Anti-PNMT/AF350 Conjugated antibody
Noradrenaline N-methyltransferase; PENT; Phenylethanolamine N-methyltransferase; PNMTase; PNMT_HUMAN.
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  • NO.:SL3912R-AF350
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Dog,Pig,Horse,Rabbit,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-PNMT/AF350
Chinese Name AF350标记的苯乙醇胺甲基转移酶抗体
Alias Noradrenaline N-methyltransferase; PENT; Phenylethanolamine N-methyltransferase; PNMTase; PNMT_HUMAN.   
Research Area Tumour  Cardiovascular  Cell biology  immunology  Neurobiology  transcriptional regulatory factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Dog, Pig, Horse, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 31kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PNMT
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Phenylethanolamine N-methyltransferase, PNMT, catalyzes the synthesis of epinephrine from norepinephrine, (adrenalin from noradrenalin), in catecholamine biosynthesis.

Function:
Converts noradrenaline to adrenaline.

Similarity:
Belongs to the NNMT/PNMT/TEMT family.

Database links:
UniProtKB/Swiss-Prot: P11086.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

PNMT又称去甲肾上腺素N-甲基转移酶,其作用;催化将甲基从S-腺苷酰甲硫氨酸转移到去甲肾上腺素的氨基端生成肾上腺素反应的酶。一般认为:嗜铬细胞胞浆中存在大量的PNMT,可使去甲肾上腺素甲基化而成肾上腺素(另一个生成肾上腺素的方式)。

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