Product Name	Anti-SLC25A10/AF350
Chinese Name	AF350标记的Mitochondrion二羧酸载体蛋白抗体
Alias	Mitochondrial dicarboxylate carrier; DIC; SLC25A10; Solute carrier family 25 member 10; DIC_HUMAN.
Research Area	Tumour  Cell biology  immunology  Chromatin and nuclear signals  transcriptional regulatory factor  Mitochondrion
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Horse, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	31kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC25A10
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The mitochondrial dicarboxylate carrier protein (mDIC) belongs to superfamily of mitochondrial transporters. It has been demonstrated that the expression of mDIC leads to hyperpolarization of the mitochondria, as well as succinate uptake by the mitochondria. It is highly expressed in adipose tissue, where its expression is downregulated by insulin and upregulated by free fatty acids. mDIC is also thought to play a role in glyceroneogenesis. Function: Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane. Subcellular Location: Mitochondrion inner membrane; Multi-pass membrane protein. Tissue Specificity: Present in high amounts in liver and kidney, and at lower levels in all the other tissues analyzed. Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family. Contains 3 Solcar repeats. Database links: UniProtKB/Swiss-Prot: Q9UBX3.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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