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Rabbit Anti-phospho-PTPRA (Ser180)/AF350 Conjugated antibody
Rabbit Anti-phospho-PTPRA (Ser180)/AF350 Conjugated antibody
PTPRA (Sphospho-er180); PTPRA (phospho-S180); p-PTPRA (Ser180); p-PTPRA (S180); HEPTP; HLPR; HPTP alpha; HPTPA; HPTPalpha; Leukocyte common antigen related peptide; LRP; Protein tyrosine phosphatase alpha; Protein tyrosine phosphatase receptor type A; Pro
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  • NO.:SL5175R-AF350
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-phospho-PTPRA (Ser180)/AF350
Chinese Name AF350标记的磷酸化酪氨酸磷酸酶α抗体
Alias PTPRA (Sphospho-er180); PTPRA (phospho-S180); p-PTPRA (Ser180); p-PTPRA (S180); HEPTP; HLPR; HPTP alpha; HPTPA; HPTPalpha; Leukocyte common antigen related peptide; LRP; Protein tyrosine phosphatase alpha; Protein tyrosine phosphatase receptor type A; Protein tyrosine phosphatase receptor type alpha polypeptide; Protein tyrosine phosphate; Protein-tyrosine phosphatase alpha; PTPA; PTPalpha; PTPase alpha; PTPLCA related phosphatase; PTPRA; PTPRA_HUMAN; PTPRL 2; PTPRL2; PTRA; R PTP alpha; R-PTP-alpha; Receptor type tyrosine protein phosphatase alpha; Receptor-type tyrosine-protein phosphatase alpha; RPTPA; Tyrosine phosphatase alpha.  
Product Type Phosphorylated anti 
Research Area immunology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 89kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated Synthesised phosphopeptide derived from human PTPRA around the phosphorylation site of Ser180
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Vital cellular functions such as cell proliferation and signal transduction are regulated in part by the balance between the activities of protein tyrosine kinases (PTK) and protein tyrosine phosphatases (PTPs). The protein contains a 121 residue extracellular domain, a single transmembrane segment, and 2 tandem intracytoplasmic catalytic domains. The PTP alpha protein is ubiquitously expressed and may play a fundamental role in the physiology of all cells.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
Contains 2 tyrosine-protein phosphatase domains.

Database links:

Entrez Gene: 5786 Human

Entrez Gene: 19262 Mouse

Entrez Gene: 25167 Rat

Omim: 176884 Human

SwissProt: P18433 Human

SwissProt: P18052 Mouse

SwissProt: Q03348 Rat

Unigene: 269577 Human

Unigene: 224246 Mouse

Unigene: 18043 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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