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Macrophage Colony-Stimulating Factor1 (M-CSF), Human, Recombinant
Brief introduction:Macrophage colony stimulating Factor 1 (M-CSF) is a hematopoietic growth factor, specifically involved in monocytogenesis. In mammals, it exists in three isomers, all of which have 32 amino acid signal peptides at the N-terminal, 149 amino acid growth factor domains, 21 amino acid residues transmembrane domains, and 37 amino acid cytoplasmic tail domains. The biological activity of human M-CSF remained within the 149 amino acid growth factor domain and was activated only as a disulfide bonded dimer, which binds to Cys 63.Recombinant Human macrophage Colony Stimulating Factor 1 (rhM-CSF) is a disulfide bonded homodimer containing two non-glycation polypeptide chains, each containing 159 amino acids with a molecular mass of 28kDa.Macrophage Colony-Stimulating Factor1(M-CSF),Human,Recombinant; Macrophage Colony Stimulating Factor; CSF-1; Lanimostim; MCSF; MGC31930; M-CSFPhysical properties and indexes:Purity: >95%Endotoxin: <1EU/μgTiter: 3.3x 105 -- 1 x106units/mgExpression host: E. coliSource: HumanPurification Method: purification by chromatographyCharacter: This product is white loose bodyStability: Freeze-dried powder can be stored at -20℃ for 12 months, dissolved liquid can be stored at -20℃ for 3 months, 2 weeks at 4℃, and avoid repeated freeze-thawAmino acid sequence:MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVDQEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQLQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKNVFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS
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