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Rabbit Anti-HFREP1 antibody
Rabbit Anti-HFREP1 antibody
FGL 1; Fgl1; FGL1_HUMAN; Fibrinogen like 1; Fibrinogen like protein 1; Fibrinogen related protein 1; Fibrinogen-like protein 1; Hepassocin; Hepatocellular carcinoma related sequence; Hepatocyte derived fibrinogen related protein 1; Hepatocyte-derived fibr
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Details

Product Name HFREP1
Chinese Name 肝细胞源性纤维蛋白原相关蛋白1/FGL1抗体
Alias FGL 1; Fgl1; FGL1_HUMAN; Fibrinogen like 1; Fibrinogen like protein 1; Fibrinogen related protein 1; Fibrinogen-like protein 1; Hepassocin; Hepatocellular carcinoma related sequence; Hepatocyte derived fibrinogen related protein 1; Hepatocyte-derived fibrinogen-related protein 1; HFREP 1; HFREP-1; HFREP1; HP 041; HP-041; HP041; LFIRE 1; LFIRE-1; LFIRE1; Liver fibrinogen related protein 1; Liver fibrinogen-related protein 1; MFIRE 1.  
Research Area Cardiovascular  Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Cow, Horse, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 32kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human HFREP1/FGL1: 251-312/312 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008].

Function:
Has hepatocyte mitogenic activity.

Subunit:
Homodimer (Probable).

Subcellular Location:
Secreted.

Tissue Specificity:
Liver specific.

Similarity:
Contains 1 fibrinogen C-terminal domain.

SWISS:
Q08830

Gene ID:
2267

Database links:

Entrez Gene: 508090 Cow

Entrez Gene: 2267 Human

Entrez Gene: 234199 Mouse

Entrez Gene: 246186 Rat

Omim: 605776 Human

SwissProt: Q3SZZ7 Cow

SwissProt: Q08830 Human

SwissProt: Q71KU9 Mouse

SwissProt: Q5M8C6 Rat

Unigene: 491143 Human

Unigene: 277955 Mouse

Unigene: 15994 Rat



Product Picture
Sample:
Liver (Mouse) Lysate at 40 ug
Primary: Anti- HFREP1 (SL6894R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kD
Observed band size: 35 kD

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