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Product Name MAGEA11 Chinese Name 黑色素瘤相关抗原11抗体 Alias Cancer/testis antigen 1.11; cancer/testis antigen family 1, member 11; CT1.11; MAGE 11; MAGE 11 antigen; MAGAB_HUMAN; MAGE11; MAGEA 11; Melanoma antigen family A 11; Melanoma associated antigen 11; MGC10511. literatures Specific References (1) | SL6817R has been referenced in 1 publications.[IF=1.89] Choudhary, Meenakshi, et al. "Enhancing Lung Cancer Diagnosis: Electrochemical Simultaneous Bianalyte Immunosensing Using Carbon Nanotubes–Chitosan Nanocomposite." Applied Biochemistry and Biotechnology (2014): 1-13. other ;Research Area Tumour Cell biology immunology Chromatin and nuclear signals Signal transduction TumourCell biologyMaker Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 48kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MAGEA11: 12-120/429 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail MAGEA11 (Melanoma antigen family A, 11) is a member of the MAGEA gene family. MAGEA proteins are expressed in melanomas and other cancers. MAGEA11 acts as androgen receptor co-regulator increasing androgen receptor activity by modulating the receptors interdomain interaction.
Function:
Acts as androgen receptor co-regulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
Subcellular Location:
Nucleus. Cytoplasm.
Tissue Specificity:
Expressed in tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma. Expressed in testis, ovary, prostate, cancerous prostate, breast and adrenal tissue.
Similarity:
Contains 1 MAGE domain.
SWISS:
P43364
Gene ID:
4110
Database links:Entrez Gene: 4110 Human
Omim: 300344 Human
SwissProt: P43364 Human
Unigene: 670252 Human
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