Product Name	ABI3BP
Chinese Name	ABI基因家族成员3Binding protein抗体
Alias	ABI gene family member 3 (NESH) binding protein; ABI gene family member 3 binding protein; ABI3BP; Nesh binding protein; Nesh BP; NESHBP; Target of Nesh SH3; TARSH; TARSH_HUMAN.
Research Area	Tumour  Cell biology  immunology  TumourCell biologyMaker
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	116kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ABI3BP: 931-1075/1075
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	ABI3BP (ABI gene family member 3-binding protein) contains 2 fibronectin type-III domains and is thought to interact with ABI3. It is expressed in brain, heart, lung, liver, pancreas, kidney and placenta. ABI3BP expression is dramatically reduced in human lung cancer cell lines and primary lung tumor, while it is predominantly expressed in normal conditions, suggesting that it is involved in prevention of tumorigenesis. Subunit: Probably interacts with ABI3. Subcellular Location: Secreted. Tissue Specificity: Expressed in brain, heart, lung, liver, pancreas kidney and placenta. Similarity: Contains 2 fibronectin type-III domains. SWISS: Q7Z7G0 Gene ID: 25890 Database links: Entrez Gene: 25890 Human Omim: 606279 Human SwissProt: Q7Z7G0 Human Unigene: 477015 Human
Product Picture	Sample: Placenta (Mouse) Lysate at 40 ug Hela(Human) Cell Lysate at 30 ug Primary: Anti- ABI3BP (SL6506R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 116 kD Observed band size: 116 kD Tissue/cell: human placenta tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-ABI3BP Polyclonal Antibody, Unconjugated(SL6506R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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