Product Name	GABA A Receptor alpha 3
Chinese Name	G氨基丁酸受体α3抗体
Alias	GABA(A) receptor subunit alpha 3; GABA(A) receptor subunit alpha-3; GABR A3; GABRA 3; GABRA-3; GABRA3; Gamma aminobutyric acid (GABA) A receptor alpha 3; Gamma aminobutyric acid A receptor alpha 3; Gamma aminobutyric acid receptor subunit alpha 3; gamma-aminobutyric acid A receptor alpha 3; Gamma-aminobutyric acid receptor subunit alpha-3; GBRA3_HUMAN.  GABA A Receptor α3; GABA A Receptor α 3; GABA A Receptor α-3; GABA A Receptor-α3;
Research Area	Cell biology  Neurobiology  Channel protein  The cell membrane受体
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	52kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GABRA3: 101-200/492 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Subunit: Binds UBQLN1. Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Subcellular Location: Cell junction; synapse; postsynaptic cell membrane; Cell membrane. Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA3 sub-subfamily. SWISS: P34903 Gene ID: 2556 Database links: Entrez Gene: 282237 Cow Entrez Gene: 492223 Dog Entrez Gene: 2556 Human Entrez Gene: 14396 Mouse Entrez Gene: 24947 Rat Omim: 305660 Human SwissProt: P10064 Cow SwissProt: P34903 Human SwissProt: P26049 Mouse SwissProt: P20236 Rat Unigene: 123024 Human Unigene: 102286 Mouse Unigene: 447666 Mouse Unigene: 10367 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GABA A Receptor alpha 3) Polyclonal Antibody, Unconjugated (SL6500R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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