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Product Name MTSS1 Chinese Name Tumour转移抑制蛋白1 Alias metastasis suppressor 1; Metastasis suppressor protein 1; Metastasis suppressor YGL 1; MIM; MIMA; MIMB; missing in metastasis; Missing in metastasis protein; MTSS 1; MTSS1_HUMAN. literatures Specific References (2) | SL6075R has been referenced in 2 publications.[IF=2.91] Chen, Qiang, et al. "Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model." Journal of cancer research and clinical oncology (2013): 1-10. WB ; Human.[IF=2.894] TingLu Ye. et al. 5-aminolevulinic acid photodynamic therapy inhibits invasion and metastasis of SCL-1 cells probably via MTSS1 and p63 gene related pathways. Photodiagn Photodyn. 2020 Dec;32:102039 FC ; Human.Research Area Tumour Chromatin and nuclear signals Signal transduction Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 82kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MTSS1: 101-200/755 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.
Function:
May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.
Subunit:
Binds to actin. Binds to the cytoplasmic domain of receptor protein tyrosine phosphatase delta.
Subcellular Location:
Cytoplasm, cytoskeleton.
Tissue Specificity:
Expressed in many tissues, including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood.
SWISS:
O43312
Gene ID:
9788
Database links:Entrez Gene: 9788 Human
Entrez Gene: 211401 Mouse
Omim: 608486 Human
SwissProt: O43312 Human
SwissProt: Q8R1S4 Mouse
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