Product Name	SH2D2A
Chinese Name	血管内皮生长因子受体相关蛋白抗体
Alias	SH2D2A/VEGF receptor associated protein SCAP; SH2 domain containing adapter protein; SH2 domain containing protein 2A; SH2 domain protein 2A; T cell specific adapter protein; T cell specific adapter protein TSAd; T cell specific adpater protein TSAd; T lymphocyte specific adaptor protein; TSAd; VEGF receptor associated protein; VRAP.
literatures	Specific References  (1)     |     SL3858R has been referenced in 1 publications. [IF=12.35] Compeer et al. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. (2018) Nat.Commun. 9:1597  IF ;  Mouse.   PubMed:29686427
Research Area	Tumour  immunology  Growth factors and hormones  vascular endothelial cell  t-lymphocyte
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg /Test ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	43kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SH2D2A: 101-200/389
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	SH2D2A is thought to be a T-cell-specific adapter protein involved in the control of T-cell activation. It may play a role in the CD4-p56-LCK-dependent signal transduction pathway and also in normal and pathological angiogenesis. Subunit: Interacts with KDR. Interacts with TXK and ITK. Subcellular Location: Cytoplasmic Tissue Specificity: SH2D2A is thought to be a T-cell-specific adapter protein involved in the control of T-cell activation. It may play a role in the CD4-p56-LCK-dependent signal transduction pathway and also in normal and pathological angiogenesis. Similarity: Contains 1 SH2 domain. SWISS: Q9NP31 Gene ID: 9047 Database links: Entrez Gene: 9047 Human Entrez Gene: 27371 Mouse Omim: 604514 Human SwissProt: Q9NP31 Human SwissProt: Q9QXK9 Mouse Unigene: 103527 Human Unigene: 86361 Mouse
Product Picture	Blank control(blue): HUVEC cells(fixed with 2% paraformaldehyde (10 min),then permeabilized with 90% ice-cold methanol for 30 min on ice). Primary Antibody:Rabbit Anti- SH2D2A antibody(SL3858R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.

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