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Rabbit Anti-MAGEA4 antibody
Rabbit Anti-MAGEA4 antibody
MAGE 4; MAGE-A4;MAGE 4 antigen; MAGE 41; MAGE 41 antigen; MAGE 4A; MAGE 4B; MAGE X2; MAGE X2 antigen; MAGE4; MAGE41; MAGE4A; MAGE4B; MAGEA 4; MAGEA4; Melanoma antigen family A 4; Melanoma associated antigen 4; Cancer/testis antigen 1.4; CT1.4.
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Details

Product Name MAGEA4
Chinese Name 黑色素瘤相关抗原4抗体
Alias MAGE 4; MAGE-A4;MAGE 4 antigen; MAGE 41; MAGE 41 antigen; MAGE 4A; MAGE 4B; MAGE X2; MAGE X2 antigen; MAGE4; MAGE41; MAGE4A; MAGE4B; MAGEA 4; MAGEA4; Melanoma antigen family A 4; Melanoma associated antigen 4; Cancer/testis antigen 1.4; CT1.4.  
Research Area Tumour  Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 35kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MAGE-A4: 110-210/317 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. At least four variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

Tissue Specificity:
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.

Similarity:
Contains 1 MAGE domain.

SWISS:
P43358

Gene ID:
4103

Database links:

Entrez Gene: 4103 Human

Entrez Gene: 17140 Mouse

Entrez Gene: 689858 Rat

Omim: 300175 Human

SwissProt: P43358 Human

Unigene: 37107 Human

Unigene: 377097 Mouse

Unigene: 218695 Rat



Product Picture
Sample:
MCF-7(Human) Cell Lysate at 30 ug
Primary: Anti-MAGEA4 (SL3645R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 35 kD
Observed band size: 35 kD

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