Product Name	LDHB
Chinese Name	乳酸脱氢酶抗体
Alias	Lactate Dehydrogenase B; Renal Carcinoma Antigen NY-REN-46; LDH Heart Subunit; EC 1.1.1.27; LDH-B; LDH-H; Epididymis Secretory Protein Li 281; Lactate Dehydrogenase H Chain; HEL-S-281; EC 1.1.1; LDHBD; TRG-5; LDHB_HUMAN;
literatures	Specific References  (1)     |     SL20294R has been referenced in 1 publications. [IF=4.486] Du Y et al. ATPR triggers acute myeloid leukaemia cells differentiation and cycle arrest via the RARα/LDHB/ERK‐glycolysis signalling axis. J Cell Mol Med. 2020 Jun; 24(12): 6952–6965.  IHC ;  mouse.   PubMed:32391634
Research Area	Cell biology  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, Pig, Cow, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	37kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LDHB: 181-250/334
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Recent studies have shown that two protein isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism, and that these C-terminally distinct isoforms have different subcellular localization. Alternatively spliced transcript variants have also been found for this gene. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Oct 2015] Function: This protein is involved in step 1 of the subpathway that synthesizes (S)-lactate from pyruvate.This subpathway is part of the pathway pyruvate fermentation to lactate, which is itself part of Fermentation. View all proteins of this organism that are known to be involved in the subpathway that synthesizes (S)-lactate from pyruvate, the pathway pyruvate fermentation to lactate and in Fermentation. Subunit: Homotetramer. Subcellular Location: Cytoplasm Similarity: Belongs to the LDH/MDH superfamily. LDH family. SWISS: P07195 Gene ID: 3945 Database links: Entrez Gene: 3945 Human Entrez Gene: 16832 Mouse Entrez Gene: 24534 Rat Omim: 150100 Human SwissProt: P07195 Human SwissProt: P16125 Mouse SwissProt: P42123 Rat Unigene: 446149 Human Unigene: 9745 Mouse Unigene: 1785 Rat
Product Picture	Sample: Heart (Mouse) Lysate at 40 ug Kidney (Mouse) Lysate at 40 ug Jurkat (Human) Lysate at 40 ug Primary: Anti-LDHB (SL20294R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 37 kD Observed band size: 37 kD

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