Product Name	PRPF4
Chinese Name	PRPF4蛋白抗体
Alias	HPRP4; HPRP4P; PRP4; PRP4 pre mRNA processing factor 4 homolog (yeast); PRP4/STK/WD splicing factor; Prp4p; U4/U6 small nuclear ribonucleoprotein Prp4; WD splicing factor Prp4; PRP4_HUMAN.
Research Area	Cell biology  Cyclin  Cell differentiation  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	58kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PRPF4: 431-522/522
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008] Function: Involved in pre-mRNA splicing. Subunit: Interacts directly with PRPF18, PPIH and PRPF3. Part of a heteromeric complex containing PPIH, PRPF3 and PRPF4 that is stable in the absence of RNA. This complex interacts with the U4/U5/U6 tri-snRNP complex. Subcellular Location: Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs. Similarity: Contains 7 WD repeats. SWISS: Q13523 Gene ID: 8899 Database links: Entrez Gene: 8899 Human Entrez Gene: 19134 Mouse Entrez Gene: 291078 Rat Omim: 602338 Human SwissProt: Q08DZ2 Cow SwissProt: Q13523 Human SwissProt: Q61136 Mouse SwissProt: Q5RKH1 Rat Unigene: 159014 Human Unigene: 10027 Mouse Unigene: 482253 Mouse Unigene: 32654 Rat
Product Picture	Sample: Raji (Human) Cell Lysate at 40 ug HepG2 (Human) Cell Lysate at 40 ug Hela (Human) Cell Lysate at 40 ug Primary: Anti-PRPF4(SL20098R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 58kD Observed band size: 58kD Sample: bone (mouse) Lysate at 40 ug lymph node (mouse) Lysate at 40 ug Primary: Anti-PRPF4(SL200098R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD

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