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Rabbit Anti-PASD1/CT63 antibody
Rabbit Anti-PASD1/CT63 antibody
Cancer/testis antigen 63; CT63; OX-TES-1; PAS domain containing 1; PAS domain-containing protein 1; PASD1; PASD1_HUMAN.
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  • NO.:SL19895R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name PASD1/CT63
Chinese Name 癌/睾丸抗原63
Alias Cancer/testis antigen 63; CT63; OX-TES-1; PAS domain containing 1; PAS domain-containing protein 1; PASD1; PASD1_HUMAN.  
Research Area Cell biology  Signal transduction  transcriptional regulatory factor  t-lymphocyte  b-lymphocyte  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 70kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PASD1/CT63: 1-100/773 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010]

Function:
May function as a transcription factor.

Subcellular Location:
Nucleus.

Tissue Specificity:
Testis-specific. Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widespread expression seen in solid tumors and diffuse large B-cell lymphoma (DLBCL)-derived cell lines. Isoform 2 is expressed in all DLBCL-derived cell lines, while isoform 1 is preferentially expressed in cell lines derived from non-germinal center DLBCL.

Similarity:
Contains 1 PAS (PER-ARNT-SIM) domain.

SWISS:
Q8IV76

Gene ID:
139135

Database links:

Entrez Gene: 139135 Human

SwissProt: Q8IV76 Human

Unigene: 160594 Human



Product Picture
Sample: MCF-7 Cell (Human) Lysate at 40 ug
Primary: Anti-PASD1/CT63 (SL19895R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 70 kD
Observed band size: 73 kD

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