Product Name	phospho-Parvin alpha (Ser8)
Chinese Name	磷酸化基质重塑相关蛋白PARVA抗体
Alias	Parvin alpha (phospho S8); p-Parvin alpha (phospho S8); Actopaxin; Alpha parvin; Alpha-parvin; Calponin like integrin linked kinase binding protein; Calponin-like integrin-linked kinase-binding protein; CH ILKBP; CH-ILKBP; FLJ10793; FLJ12254; Matrix remodelling associated 2; Matrix remodelling associated protein 2; Matrix-remodeling-associated protein 2; MXRA 2; MXRA2; PARV A; PARVA; PARVA_HUMAN.
Product Type	Phosphorylated anti
Research Area	Cell biology  Signal transduction  Binding protein  Cytoskeleton
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Cow, Rabbit, )
Applications	WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	42kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthesised phosphopeptide derived from human Parvin alpha around the phosphorylation site of Ser8: QK(p-S)PS
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010] Function: Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Plays a role in ciliogenesis. Subcellular Location: Cell junction > focal adhesion. Cell membrane. Cytoplasm > cytoskeleton. Constituent of focal adhesions. Tissue Specificity: Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. Similarity: Belongs to the parvin family. Contains 2 CH (calponin-homology) domains. SWISS: Q9NVD7 Gene ID: 55742 Database links: Entrez Gene: 55742 Human Entrez Gene: 57342 Mouse Entrez Gene: 57341 Rat Omim: 608120 Human SwissProt: Q9NVD7 Human SwissProt: Q9EPC1 Mouse SwissProt: Q9HB97 Rat Unigene: 432914 Human Unigene: 143763 Mouse Unigene: 92564 Rat
Product Picture	Sample: Embryo (Mouse) Lysate at 40 ug Primary: Anti-phospho-Parvin alpha (Ser8) (SL19894R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD

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