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Product Name SLC25A26 Chinese Name 溶质载体家族蛋白25成员A26抗体 Alias Mitochondrial S-adenosylmethionine transporter; S-adenosylmethionine mitochondrial carrier protein; SAMC; SAMC_HUMAN; slc25a26; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 26; Solute carrier family 25 member 26. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Cow, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 29kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC25A26: 101-200/274 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Mitochondrial carriers, including SLC25A26, are a family of transport proteins found mostly in the inner membranes of mitochondria. They shuttle metabolites and cofactors through the mitochondrial membrane (Agrimi et al., 2004 [PubMed 14674884]).[supplied by OMIM, Mar 2008]
Function:
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. Specifically mediates the transport of S-adenosylmethionine (SAM) into the mitochondria.
Subcellular Location:
Mitochondrion inner membrane.
Tissue Specificity:
Widely expressed. Highly expressed in testis, with moderate expression in brain, heart, kidney, lung, skeletal muscle, pancreas, small intestine and liver, and low expression in spleen.
Similarity:
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.
SWISS:
Q70HW3
Gene ID:
115286
Database links:
Entrez Gene: 100719522 Guinea pig
Entrez Gene: 115286 Human
Entrez Gene: 67582 Mouse
Entrez Gene: 100147801 Sheep
Entrez Gene: 560478 Zebrafish
Omim: 611037 Human
SwissProt: Q70HW3 Human
SwissProt: Q5U680 Mouse
SwissProt: Q4V9P0 Zebrafish
Unigene: 379386 Human
Unigene: 280725 Mouse
Unigene: 96303 Rat
Product Picture Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-SLC25A26 Polyclonal Antibody, Unconjugated(SL19813R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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