Product Name	SLC34A1
Chinese Name	溶质载体家族蛋白34成员A1抗体
Alias	FRTS2; Na(+)-dependent phosphate cotransporter 2A; Na(+)/Pi cotransporter 2A; Na+-phosphate cotransporter type II; naPi-2a; NAPI-3; naPi2a; NAPI3; NPHLOP1; NPT2; NPTIIa; renal sodium-dependent phosphate transporter; renal sodium/phosphate transporter protein 2; SLC11; SLC17A2; SLC17A2, formerly; NPT2A_HUMAN; sodium-dependent phosphate transport protein 2A; sodium-phosphate transport protein 2A; sodium/phosphate co-transporter; sodium/phosphate cotransporter 2A; sodium/phosphate transporter 2, kidney; solute carrier family 17 (sodium phosphate), member 2; solute carrier family 17, member 2, formerly; solute carrier family 34 (sodium phosphate), member 1; solute carrier family 34 (type II sodium/phosphate.
Research Area	Cell biology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,  (predicted: Mouse, Pig, Rabbit, Sheep, Cat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	69kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC34A1: 101-200/639 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009] Function: May be involved in actively transporting phosphate into cells via Na+ cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx. Subunit: Interacts via its C-terminal region with PDZK2 (By similarity). Interacts with SLC9A3R1. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Kidney and lung. DISEASE: The disease is caused by mutations affecting the gene represented in this entry. Disease description:A disease characterized by decreased renal phosphate absorption, renal phosphate wasting, hypophosphatemia, hyperphosphaturia, hypercalciuria, nephrolithiasis and osteoporosis. Similarity: Belongs to the SLC34A transporter family. SWISS: Q06495 Gene ID: 6569 Database links: Entrez Gene: 282483 Cow Entrez Gene: 100735387 Guinea pig Entrez Gene: 100058397 Horse Entrez Gene: 6569 Human Entrez Gene: 20505 Mouse Entrez Gene: 100155735 Pig Entrez Gene: 733703 Pig Entrez Gene: 100009392 Rabbit Entrez Gene: 25548 Rat Entrez Gene: 443505 Sheep Omim: 182309 Human SwissProt: Q06495 Human SwissProt: Q60825 Mouse SwissProt: Q28620 Rabbit SwissProt: Q06496 Rat SwissProt: O97704 Sheep Unigene: 936 Human Unigene: 276355 Mouse Unigene: 92022 Rat
Product Picture	Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-SLC34A1 Polyclonal Antibody, Unconjugated(SL19812R) 1:600, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining Tissue/cell: rat lung tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-SLC34A1 Polyclonal Antibody, Unconjugated(SL19812R) 1:600, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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