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Rabbit Anti-SLC25A25 antibody
Rabbit Anti-SLC25A25 antibody
Calcium-binding mitochondrial carrier protein SCaMC-2; KIAA1896; MCSC; MGC105138; MGC119514; MGC119515; MGC119516; MGC119517; Mitochondrial ATP Mg/Pi carrier; Mitochondrial ATP-Mg/Pi carrier protein 3; Mitochondrial Ca(2+)-dependent solute carrier protein
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  • NO.:SL19811R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Guinea Pig,Cat,)
    Applications:WB ELISA
    concentration:1mg/ml
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Product Name SLC25A25
Chinese Name 溶质载体家族蛋白25成员A25抗体
Alias Calcium-binding mitochondrial carrier protein SCaMC-2; KIAA1896; MCSC; MGC105138; MGC119514; MGC119515; MGC119516; MGC119517; Mitochondrial ATP Mg/Pi carrier; Mitochondrial ATP-Mg/Pi carrier protein 3; Mitochondrial Ca(2+)-dependent solute carrier protein 3; Mitochondrial Ca2+ dependent solute carrier; Mitochondrial calcium-dependent solute carrier; PCSCL; RP11 395P17.4; SCAMC 2; SCAMC2; SCMC2_HUMAN; Short calcium binding mitochondrial carrier 2; SLC25A25; Small calcium binding mitochondrial carrier 2; Small calcium-binding mitochondrial carrier protein 2; Solute carrier family 25 (mitochondrial carrier phosphate carrier) member 25; Solute carrier family 25 member 25; solute carrier family 25, member 25, isoform a.  
Research Area Tumour  Cell biology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 52kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SLC25A25: 1-100/469 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012]

Function:
Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria.

Subcellular Location:
Mitochondrion inner membrane.

Tissue Specificity:
Present in various cell lines (at protein level). Widely expressed. Expressed in fetal and adult liver, skeletal muscle, testis, ovary, hippocampus and caudate nucleus. Isoform 1 is present in all tissues tested. Isoform 2 expression is restricted to kidney and lung.

Similarity:
Belongs to the mitochondrial carrier family.
Contains 3 EF-hand domains.
Contains 3 Solcar repeats.

SWISS:
Q6KCM7

Gene ID:
114789

Database links:

Entrez Gene: 527786 Cow

Entrez Gene: 114789 Human

Entrez Gene: 227731 Mouse

Entrez Gene: 246771 Rat

Entrez Gene: 406541 Zebrafish

Omim: 608745 Human

SwissProt: Q0V7M4 Cow

SwissProt: Q6KCM7 Human

SwissProt: A2ASZ8 Mouse

SwissProt: Q8K3P6 Rat

SwissProt: A2CEQ0 Zebrafish

Unigene: 5476 Human

Unigene: 37395 Mouse

Unigene: 473265 Mouse

Unigene: 17644 Rat



Product Picture
Sample:muscle (Mouse) Lysate at 40 ug
Primary: Anti-SLC25A25(SL19811R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 52kD
Observed band size: 60kD

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