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Product Name ONECUT2 Chinese Name 转录因子ONECUT2抗体 Alias HGNC:8139; MGC120377; MGC120378; OC 2; OC2; one cut domain family member 2; ONECUT 2; ONECUT 2 homeodomain transcription factor; ONECUT 2 protein; ONECUT2 homeodomain transcription factor; ONECUT2 protein; Transcription factor ONECUT 2; Transcription factor ONECUT2. literatures Specific References (1) | SL19643R has been referenced in 1 publications.[IF=11.161] Zhipeng Jiang. et al. EIF4A3-induced circ_0084615 contributes to the progression of colorectal cancer via miR-599/ONECUT2 pathway. J Exp Clin Canc Res. 2021 Dec;40(1):1-15 WB,IHC ; Human.Research Area Cell biology transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, ) Applications WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 52kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ONECUT2: 401-504/504 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008]
Function:
Transcriptional activator. Activates the transcription of a number of liver genes such as HNF3B.
Subcellular Location:
Nuclear
Similarity:
Belongs to the CUT homeobox family.
SWISS:
O95948
Gene ID:
9480
Database links:Entrez Gene: 9480 Human
Entrez Gene: 225631 Mouse
Omim: 604894 Human
SwissProt: O95948 Human
SwissProt: Q6XBJ3 Mouse
Unigene: 194725 Human
Unigene: 118978 Mouse
Product Picture Sample:Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-ONECUT2 (SL19643R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
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