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Product Name OLFML2A Chinese Name 嗅介蛋白样蛋白2A抗体 Alias FLJ00237; Olfactomedin like 2A; Olfactomedin like protein 2A; OLM2A_HUMAN; Photomedin 1; PRO34319; UNQ9394/PRO34319. Research Area Cell biology Neurobiology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat, ) Applications IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 65kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OLFML2A: 501-600/652 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail OLFML2A contains one olfactomedin-like domain. Its exact function is unknown. There are three named isoforms produced by alternative splicing.
Subunit:
Homodimer. Binds to heparin and chondroitin sulfate E.
Subcellular Location:
Secreted
Tissue Specificity:
In the kidney expressed only by podocytes, wherein they localize to major processes.
DISEASE:
Detected at the vesicle stage of developing glomeruli, expressed in invading endothelial cells in the glomerular cleft at the S-shaped stage and is later expressed only at the basal aspect of maturing podocytes.
SWISS:
Q68BL7
Gene ID:
169611
Database links:Entrez Gene: 169611 Human
Entrez Gene: 241327 Mouse
SwissProt: Q68BL7 Human
SwissProt: Q8BHP7 Mouse
Unigene: 357004 Human
Unigene: 103491 Mouse
Unigene: 144357 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (OLFML2A) Polyclonal Antibody, Unconjugated (SL19639R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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