Product Name	SEC61A
Chinese Name	TransporterSEC61A抗体
Alias	chunp6898; fb62c11; HSEC61; protein transport protein SEC61 alpha subunit; protein transport protein Sec61 subunit alpha; Protein transport protein Sec61 subunit alpha isoform 1; S61A1_HUMAN; SEC 61; SEC 61A; Sec61 alpha 1; Sec61 alpha 1 subunit; Sec61 alpha 1 subunit (S. cerevisiae); Sec61 alpha-1; SEC61; Sec61 homolog; SEC61A1; sec61aa.
Research Area	Cell biology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, Dog, Cow, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	52kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SEC61A: 181-280/476
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008] Function: Plays a crucial role in the insertion of secretory and membrane polypeptides into the ER. Required for assembly of membrane and secretory proteins. Tightly associated with membrane-bound ribosomes, either directly or through adapter proteins. Subunit: Heterotrimeric complex composed of SEC61-alpha, SEC61-beta and SEC61-gamma. Subcellular Location: Endoplasmic reticulum membrane. Similarity: Belongs to the secY/SEC61-alpha family. SWISS: P61619 Gene ID: 29927 Database links: Entrez Gene: 29927 Human Entrez Gene: 505064 Cow Entrez Gene: 404006 Dog Entrez Gene: 53421 Mouse Entrez Gene: 80843 Rat Entrez Gene: 192298 Zebrafish Omim: 609213 Human SwissProt: Q5EA68 Cow SwissProt: P38377 Dog SwissProt: P61619 Human SwissProt: P61620 Mouse SwissProt: P61621 Rat SwissProt: Q90ZM2 Zebrafish Unigene: 518236 Human Unigene: 28375 Mouse Unigene: 485032 Mouse Unigene: 47029 Rat Unigene: 51503 Zebrafish
Product Picture	Sample: A431(Human) Cell Lysate at 30 ug Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-SEC61A (SL19618R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD

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