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Rabbit Anti-NOLC1 antibody
Rabbit Anti-NOLC1 antibody
140 kDa nucleolar phosphoprotein; HCV NS5A trans regulated protein 13; HCV NS5A transactivated protein 13; HCV NS5A-transactivated protein 13; Hepatitis C virus NS5A transactivated protein 13; Hepatitis C virus NS5A-transactivated protein 13; KIAA0035; NO
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  • NO.:SL19315R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:ELISA
    concentration:1mg/ml
  • Goods click count:19
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Details

Product Name NOLC1
Chinese Name 丙型肝炎病毒NS5A反式蛋白13抗体
Alias 140 kDa nucleolar phosphoprotein; HCV NS5A trans regulated protein 13; HCV NS5A transactivated protein 13; HCV NS5A-transactivated protein 13; Hepatitis C virus NS5A transactivated protein 13; Hepatitis C virus NS5A-transactivated protein 13; KIAA0035; NOLC 1; NOLC1; NOLC1_HUMAN; NOPP 130; NOPP 140; NOPP130; Nopp140; NS5ATP13; Nucleolar 130 kDa protein; Nucleolar and coiled body phosphoprotein 1; Nucleolar and coiled body phosphprotein 1; Nucleolar and coiled-body phosphoprotein 1; Nucleolar phosphoprotein p130; Nucleolar protein p130; P130.  
Research Area Cell biology  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 74kDa
Cellular localization The nucleus cytoplasmic 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human NOLC1: 621-699/699 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.

Subcellular Location:
Nucleus > nucleolus. Cytoplasm. Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase.

Post-translational modifications:
Undergoes rapid and massive phosphorylation/dephosphorylation cycles on CK2 and PKC sites. There is evidence suggesting that CDK1 kinase phosphorylates p130 at the M-phase.

Similarity:
Contains 1 LisH domain.

SWISS:
Q14978

Gene ID:
9221

Database links:

Entrez Gene: 9221 Human

Entrez Gene: 609496 Dog

Entrez Gene: 70769 Mouse

Entrez Gene: 64896 Rat

Omim: 602394 Human

SwissProt: Q14978 Human

SwissProt: P41777 Rat

Unigene: 523238 Human

Unigene: 402190 Mouse

Unigene: 9517 Rat



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