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Product Name GPR50/Melatonin Related Receptor Chinese Name 褪黑激素相关受体抗体 Alias G protein coupled receptor 50; G protein-coupled receptor 50; GPR 50; Gpr50; H9; Mel1c; Melatonin-related receptor; MGC125342; MTNRL; MTR1L_HUMAN. Research Area Neurobiology G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Horse, Rabbit, Cat, ) Applications WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 67kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GPR50/Melatonin Related Receptor: 1-100/617 <Cytoplasmic> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
Subcellular Location:
Cell membrane.
Tissue Specificity:
Hypothalamus and pituitary.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
Q13585
Gene ID:
9248
Database links:
Entrez Gene: 9248 Human
Omim: 300207 Human
SwissProt: Q13585 Human
Unigene: 567390 Human
Unigene: 92385 Rat
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