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Rabbit Anti-MAP3K6/ASK2 antibody
Rabbit Anti-MAP3K6/ASK2 antibody
apoptosis signal regulating kinase 2; Apoptosis signal-regulating kinase 2; ASK2; EC 2.7.11.25; M3K6_HUMAN; MAP3K6; MAPKKK6; MEKK6; MGC125653; MGC20114; Mitogen-activated protein kinase kinase kinase 6.
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  • NO.:SL18665R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Human,Rat,Dog,Horse,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name MAP3K6/ASK2
Chinese Name Apoptosis信号调节激酶2抗体
Alias apoptosis signal regulating kinase 2; Apoptosis signal-regulating kinase 2; ASK2; EC 2.7.11.25; M3K6_HUMAN; MAP3K6; MAPKKK6; MEKK6; MGC125653; MGC20114; Mitogen-activated protein kinase kinase kinase 6.  
Research Area Cell biology  Signal transduction  Kinases and Phosphatases  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Dog, Horse, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 143kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MAP3K6/ASK2: 101-200/1288 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a serine/threonine protein kinase that forms a component of protein kinase-mediated signal transduction cascades. The encoded kinase participates in the regulation of vascular endothelial growth factor (VEGF) expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Function:
Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.

Similarity:
Belongs to the protein kinase superfamily.
STE Ser/Thr protein kinase family.
MAP kinase kinase kinase subfamily.
Contains 1 protein kinase domain.

SWISS:
O95382

Gene ID:
9064

Database links:

Entrez Gene: 9064 Human

Entrez Gene: 53608 Mouse

Entrez Gene: 53608 Rat

Omim: 604468 Human

SwissProt: O95382 Human

SwissProt: Q9WTR2 Mouse

SwissProt: D3ZFL3 Rat

Unigene: 194694 Human

Unigene: 36640 Mouse



Product Picture
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MAP3K6) Polyclonal Antibody, Unconjugated (SL18665R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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