Product Name	LRP11
Chinese Name	低密度Lipoprotein受体相关蛋白11抗体
Alias	bA350J20.3; Low density lipoprotein receptor related protein 11; LRP 11; MANSC3.
Research Area	Tumour  Cell biology  immunology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	49kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LRP11: 341-440/500 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	LRP11 is a 500 amino acid single-pass type I membrane protein that exists as two alternatively spliced isoforms. LRP11 is encoded by a gene located on human chromosome 6q25.1. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. Function: LRP11 belongs to the LDLR family. It contains one LDL-receptor class A domain, one MANEC domain and one PKD domain. There are two named isoforms. Subcellular Location: Membrane; Single pass type I membrane protein Similarity: Belongs to the LDLR family. Contains 1 LDL-receptor class A domain. Contains 1 MANSC domain. Contains 1 PKD domain. SWISS: Q86VZ4 Gene ID: 84918 Database links: Entrez Gene: 84918 Human SwissProt: Q86VZ4 Human
Product Picture	Sample: 293T(Human) Cell Lysate at 30 ug Primary: Anti-LRP11 (SL18361R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kD Observed band size: 49 kD

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