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Product Name Camk1g Chinese Name 钙/钙调蛋白依赖蛋白激酶IG抗体 Alias Calcium/calmodulin dependent protein kinase 1 G; Calcium/calmodulin-dependent protein kinase type 1G; CaM kinase I gamma; CaM kinase IG; CaM-KI gamma; CaMKI gamma; CAMK1G; VWS1; CaMKI-gamma; CaMKIG; CaMK-like CREB kinase III; CLICK III; KCC1G_HUMAN. Research Area Cell biology Neurobiology Signal transduction Growth factors and hormones Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 53kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Camk1g: 381-476/476 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail CaMKI gamma is a Calcium/calmodulin-dependent protein kinase which belongs to a proposed calcium-triggered signaling cascade. In vitro it phosphorylates transcription factor CREB1. It has been proposed that CaMKI gamma is involved in dendritic outgrowth mediated by CaM-dependant protein kinase kinase.
Function:
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1 (By similarity).
Subcellular Location:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
Tissue Specificity:
Mainly expressed in brain with small amounts in skeletal muscles, kidney, spleen and liver. Strongly expressed in forebrain neocortex, striatum and limbic system.
Post-translational modifications:
May be prenylated on Cys-473.
Similarity:
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. Contains 1 protein kinase domain.
SWISS:
Q96NX5
Gene ID:
57172
Database links:Entrez Gene: 57172 Human
Entrez Gene: 215303 Mouse
SwissProt: Q96NX5 Human
SwissProt: Q91VB2 Mouse
Unigene: 199068 Human
Unigene: 40329 Mouse
Unigene: 91453 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Camk1g) Polyclonal Antibody, Unconjugated (SL1809R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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