Product Name	MRGX3
Chinese Name	G protein-coupled receptorMRGX3抗体
Alias	G protein coupled receptor SNSR1; G protein coupled receptor SNSR2; G protein-coupled receptor MRGX 3; G protein-coupled receptor MRGX3; GPCR; Mas related GPCR member X3; Mas-related G protein coupled MRGX 3; Mas-related G protein coupled MRGX3; Mas-related G-protein coupled receptor member X3; MAS-related GPR, member X3; MRGPRX3; MRGX3; MRGX3_HUMAN; Sensory neuron-specific G-protein coupled receptor 1; Sensory neuron-specific G-protein coupled receptor 1/2; SNSR1; SNSR2.
Research Area	Cell biology  immunology  Neurobiology  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	36kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MRGX3: 51-150/322 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009] Function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Subcellular Location: Cell membrane. Tissue Specificity: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. SWISS: Q96LB0 Gene ID: 117195 Database links: Entrez Gene: 117195 Human Omim: 607229 Human SwissProt: Q96LB0 Human Unigene: 380177 Human
Product Picture	Tissue/cell: human brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-MRGX3 Polyclonal Antibody, Unconjugated(SL17762R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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