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Product Name SGK196 Chinese Name SGK196蛋白抗体 Alias FLJ23356; MDDGA12; Probable inactive protein kinase-like protein SgK196; Protein kinase like protein SgK196; Protein kinase-like protein SgK196; SGK196; Sugen kinase 196. Research Area Cell biology Signal transduction Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 40kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SGK196: 151-250/350 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Function:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.
Subcellular Location:
Cell Membrane
SWISS:
Q9H5K3
Gene ID:
615247
Database links:Entrez Gene: 84197 Human
Omim: 615247 Human
SwissProt: Q9H5K3 Human
SwissProt: Q3TUA9 Mouse
Unigene: 491646 Human
Unigene: 39247 Rat
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