Product Name	INPP5A
Chinese Name	聚磷酸肌醇磷酸酶5A抗体
Alias	43 kDa inositol polyphosphate 5-phophatase; 5-trisphosphate 5-phosphatase; 5PTase; CTCL tumor antigen HD-CL-02; DKFZp434A1721; I5P1; I5P1_HUMAN; Inositol polyphosphate 5 phosphatase; inositol polyphosphate-5-phosphatase A; inositol trisphosphate-5-phosphatase; INPP5A; INPP5A inositol polyphosphate-5-phosphatase; InsP3 5-phosphatase; MGC116947; MGC116949; Type I inositol-1; type I inositol-1,4,5-trisphosphate 5-phophatase.
Research Area	Cell biology  Neurobiology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, )
Applications	WB=1:500-2000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	48kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human INPP5A: 31-130/412
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008] Function: Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction. Subcellular Location: Membrane. Tissue Specificity: Brain; high level in Purkinje cells. Similarity: Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type I family. SWISS: Q14642 Gene ID: 3632 Database links: Entrez Gene: 3632 Human Entrez Gene: 403937 Dog Entrez Gene: 212111 Mouse Entrez Gene: 365382 Rat Omim: 600106 Human SwissProt: Q29467 Dog SwissProt: Q14642 Human Unigene: 523360 Human Unigene: 715308 Human Unigene: 28308 Mouse Unigene: 8618 Rat
Product Picture	Sample: LOVO Cell (Human) Lysate at 40 ug Primary: Anti-INPP5A (SL16670R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kD Observed band size: 46 kD

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