Product Name	Genethonin 1
Chinese Name	淀粉结合域蛋白1抗体
Alias	FLJ41801; Genethonin-1; Genethonin1; GENEX 3414; GENEX3414; GENX 3414; GENX3414; Starch binding domain 1; Starch binding domain containing protein 1; Starch-binding domain-containing protein 1; STBD 1; STBD1; STBD1_HUMAN.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	39kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Genethonin 1: 1-100/358 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Genethonin-1 is a 358 amino acid single-pass type III membrane protein that contains one CBM20 (carbohydrate binding type-20) domain. A hydrophobic protein, Genethonin-1 is highly expressed in cardiac and skeletal muscle and is found at moderate levels in placenta and liver. Genethonin-1 and is thought to function in carbohydrate binding. The gene encoding Genethonin-1 maps to human chromosome 4, which represents approximately 6% of the human genome, contains nearly 900 genes and is associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Function: May have the capability to bind to carbohydrates. Subcellular Location: Membrane. Distributed in the transverse tubules and/or near the junctional sarcoplasmic reticulum. Tissue Specificity: Expressed at high level in skeletal and cardiac muscles. Moderately expressed in liver and placenta. No expression is found in pancreas, kidney or lung. Present in skeletal muscle, heart and placenta (at protein level). Similarity: Contains 1 CBM20 (carbohydrate binding type-20) domain. SWISS: O95210 Gene ID: 8987 Database links: Entrez Gene: 8987 Human Omim: 607406 Human SwissProt: O95210 Human Unigene: 109590 Human Unigene: 720509 Human
Product Picture	Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Gemin 7 Polyclonal Antibody, Unconjugated(SL13330R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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