Product Name	NUP107
Chinese Name	核孔复合体蛋白抗体
Alias	107 kDa nucleoporin; NPC proteins; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP 107; NUP 84; NUP84.
literatures	Specific References  (1)     |     SL11678R has been referenced in 1 publications. [IF=5.182] Wei Lv. et al. Demonstration of intracellular trafficking, cytosolic bioavailability, and target manipulation of an antibody delivery platform. Nanomed-Nanotechnol. 2021 Feb;32:102315  IF ;  Human.   PubMed:33065253
Research Area	Chromatin and nuclear signals  Neurobiology  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Pig, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 Flow-Cyt=3μg/Test  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	106kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Nuclear Pore Complex Proteins: 501-600/925
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] Function: Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex. Subunit: Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus. Subcellular Location: Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the nucleoporin Nup84/Nup107 family. SWISS: P57740 Gene ID: 57122 Database links: Entrez Gene: 57122 Human Entrez Gene: 103468 Mouse Entrez Gene: 116555 Rat Omim: 607617 Human SwissProt: P57740 Human SwissProt: Q3TT06 Mouse SwissProt: Q3V395 Mouse SwissProt: Q569X8 Mouse SwissProt: Q8BH74 Mouse SwissProt: P52590 Rat Unigene: 524574 Human Unigene: 12568 Mouse Unigene: 11398 Rat
Product Picture	Sample: 293T Cell (Human) Lysate at 30 ug Primary: Anti- Nuclear Pore Complex Proteins'Nup107 (SL11678R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 106kD Observed band size: 106kD Blank control(blue): 293T(fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice). Primary Antibody: Rabbit Anti-Nuclear Pore Complex Proteins/Nup107/AF488 Conjugated antibody (SL11678R-AF488), Dilution: 5μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG/AF488(orange) ,used under the same conditions.

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