Product Name	ALS2CR3
Chinese Name	肌萎缩侧索硬化症相关蛋白3抗体
Alias	ALS2CR3; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 3; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;TRAK2_HUMAN; Trafficking kinesin-binding protein 2.
Research Area	Cell biology  Neurobiology  Alzheimer's
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Sheep, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	101kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ALS2CR3: 701-800/914
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	ALS2CR3 may regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR. Function: May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR Subunit: Interacts with GABA-A receptor and O-GlcNAc transferase. Interacts with HGS (By similarity). Interacts with RHOT1/Miro-1 and RHOT2/Miro-2. Subcellular Location: Cytoplasm (By similarity). Early endosome (By similarity). Mitochondrion (By similarity). Note=Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner Tissue Specificity: Widely expressed, with highest expression in heart. Post-translational modifications: O-glycosylated Similarity: Contains 1 HAP1 N-terminal domain. SWISS: O60296 Gene ID: 66008 Database links: Entrez Gene: 66008 Human Entrez Gene: 70827 Mouse Omim: 607334 Human SwissProt: O60296 Human Unigene: 152774 Human Unigene: 222887 Mouse
Product Picture	Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-ALS2CR3 (SL11650R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 101 kD Observed band size: 101 kD

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