Product Name	APPBP2
Chinese Name	β淀粉样蛋白前体蛋白Binding protein2抗体
Alias	amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Ara67 Protein interacting with APP tail 1.
Research Area	immunology  Neurobiology  Alzheimer's
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	67kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human APPBP2: 201-300/585
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008]. Function: May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface. Subunit: Binds APP. Subcellular Location: Nucleus. Cytoplasm Post-translational modifications: Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP. Similarity: Contains 8 TPR repeats. SWISS: Q92624 Gene ID: 10513 Database links: Entrez Gene: 10513 Human Entrez Gene: 66884 Mouse Entrez Gene: 303396 Rat Entrez Gene: 417645 Chicken Omim: 605324 Human SwissProt: Q92624Human SwissProt: Q9DAX9 Mouse SwissProt: A5HK05 Rat Unigene: 84084 Human Unigene: 271997 Mouse Unigene: 104856 Rat

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