Product Name	NAT8 + NAT8B
Chinese Name	N-乙酰转移酶8抗体
Alias	NAT8+NAT8B; Camello-like protein 1; NAT8; NAT8_HUMAN; Probable N-acetyltransferase 8; Camello like protein 2; Camello-like protein 2; CML2; Hcml2; N acetyltransferase 8B; NAT8B; NAT8B_HUMAN; NAT8BP; Probable N acetyltransferase 8B; Probable N-acetyltransferase 8B.
Research Area	Tumour  Cell biology  Developmental biology  Signal transduction  Cyclin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	26kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NAT8: 141-227/227
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	NAT8 gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene. [provided by RefSeq, Sep 2008]. NAT8B protein encoded by this gene is highly similar to the N-acetyltransferase 8 (NAT8) gene product, which is a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and may represent a pseudogene of NAT8. This gene contains two polymorphic nonsense mutations that disrupt the active site of the protein. The full-length product of this gene contains a complete acetyltransferase domain and is identical in length to NAT8. [provided by RefSeq, Jul 2008]. Function: Plays a role in regulation of gastrulation. Subcellular Location: Membrane. Tissue Specificity: Expression is restricted to liver and kidney. Similarity: Belongs to the camello family. Contains 1 N-acetyltransferase domain. SWISS: Q9UHE5 Gene ID: 9027 Database links: Entrez Gene: 9027 Human Entrez Gene: 51471 Human NCBI: NP_057431 Human Omim: 606716 Human Omim: 608190 Human SwissProt: Q9UHE5 Human SwissProt: Q9UHF3 Human Unigene: 14637 Human Unigene: 728429 Human
Product Picture	Blank control: Hepg2 Cells(blue). Primary Antibody: Rabbit Anti-NAT8 + NAT8B/AF488 Conjugated antibody (SL11591R-AF488), Dilution: 5μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG/FITC(orange) ,used under the same conditions.

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