Product Name	ENTPD2
Chinese Name	CD39样蛋白1抗体
Alias	CD39 antigen like 1; CD39 antigen-like 1; CD39 like1; CD39L1; CD39like1; ecto ATP diphosphohydrolase 2; ecto ATPase 2; ecto ATPDase 2; Ecto-ATP diphosphohydrolase 2; Ecto-ATPase 2; Ecto-ATPDase 2; ectoATPase 2; ectoATPDase 2; Ectonucleoside triphosphate diphosphohydrolase 2; ENTP2_HUMAN; Entpd2; NTPDase 2; NTPDase2.
Research Area	Tumour  Cell biology  Neurobiology  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Rat,  (predicted: Human, Mouse, Chicken, Cow, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	54kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ENTPD2/CD39L1: 401-495/495 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. CD39L1 is a 495 amino acid multi-pass membrane protein that requires calcium and magnesium cofactors to hydrolyze ATP and other nucleotides in the regulation of purigenic neurotransmission. CD39L1 is expressed in kidney, colon, heart, testis, pancreas, brain, prostate, skeletal muscle, small intestine and ovaries. There are two isoforms of CD39L1 that are produced as a result of alternative splicing events. Function: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. Subcellular Location: Membrane; Multi-pass membrane protein Tissue Specificity: Brain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes. Similarity: Belongs to the GDA1/CD39 NTPase family. SWISS: Q9Y5L3 Gene ID: 954 Database links: Entrez Gene: 954 Human Entrez Gene: 12496 Mouse Entrez Gene: 64467 Rat Omim: 602012 Human SwissProt: Q9Y5L3 Human SwissProt: O55026 Mouse SwissProt: O35795 Rat Unigene: 123036 Human Unigene: 482100 Mouse Unigene: 8276 Rat
Product Picture	Sample: Cerebrum (Rat) Lysate at 40 ug Primary: Anti- ENTPD2 (SL11515R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kD Observed band size: 54 kD

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