Product Name	Synaptogyrin 4
Chinese Name	神经细胞囊泡循环蛋白4抗体
Alias	SNG4_HUMAN; Synaptogyrin-4; Synaptogyrin4; Synaptogyrin 4; SYNGR4; MGC125805.
Research Area	Cell biology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	26kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Synaptogyrin 4: 111-200/234
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The synaptogyrin family of proteins are integral membrane proteins containing four transmembrane regions. Synaptogyrins are tyrosine-phosphorylated proteins with two neuronal (Synaptogyrins 1 and 3) and one ubiquitous (Synaptogyrin-2) isoform. Synaptophysin and synaptogyrin represent the major constituents of synaptic vesicles. The 26kDa protein Synaptogyrin-1 is associated with presynaptic vesicles in neuronal cells. Synaptogyrin-2, also known as Cellugyrin has a tyrosine phosphorylated C-terminal cytoplasmic tail, and is involved in the regulation of membrane traffic in non-neuronal cells. Synaptogyrin-3 is expressed mainly in brain and placenta. The SYNGR4 gene encodes for the 234 amino acid protein Synaptogyrin-4. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the synaptogyrin family. Contains 1 MARVEL domain. SWISS: O95473 Gene ID: 23546 Database links: Entrez Gene: 23546 Human Entrez Gene: 58867 Mouse Entrez Gene: 292916 Rat Omim: 608373 Human SwissProt: O95473 Human SwissProt: Q9Z1L2 Mouse Unigene: 408333 Human Unigene: 214217 Mouse Unigene: 276330 Mouse
Product Picture	Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti- Synaptogyrin 4 (SL11375R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26 kD Observed band size: 25 kD

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