Product Name	SNAP23
Chinese Name	突触相关蛋白23抗体
Alias	SNAP 23; SNAP-23; SNAP23; SNAP23A; SNAP23B; SNP23_HUMAN; Synaptosomal associated protein 23; Synaptosomal associated protein 23kDa; Synaptosomal associated protein; Synaptosomal-associated protein 23; Vesicle membrane fusion protein SNAP 23; Vesicle membrane fusion protein SNAP23; Vesicle-membrane fusion protein SNAP-23; HsT17016.
Research Area	Neurobiology  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	23kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SNAP23: 101-200/211
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. Function: Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. Subunit: Homotetramer (via coiled-coil domain), also forms heterotetramers with STX4 and VAMP3. Binds simultaneously to SNAPIN and SYN4. Found in a complex with VAMP8 and STX4 in pancreas. Interacts with STX1A and STX12 (By similarity). Binds tightly to multiple syntaxins and synaptobrevins/VAMPs. Found in a complex with VAMP8 and STX1A. Subcellular Location: Cell membrane. Cell membrane. Cell junction > synapse > synaptosome. Mainly localized to the plasma membrane. Tissue Specificity: Ubiquitous. Highest levels where found in placenta. Similarity: Belongs to the SNAP-25 family. Contains 2 t-SNARE coiled-coil homology domains. SWISS: O00161 Gene ID: 8773 Database links: Entrez Gene: 453365 Chimpanzee Entrez Gene: 522423 Cow Entrez Gene: 478268 Dog Entrez Gene: 101141000 Gorilla Entrez Gene: 8773 Human Entrez Gene: 20619 Mouse Entrez Gene: 100174679 Orangutan Entrez Gene: 64630 Rat Omim: 602534 Human SwissProt: O00161 Human SwissProt: O09044 Mouse SwissProt: O70377 Rat Unigene: 511149 Human Unigene: 245715 Mouse Unigene: 14789 Rat

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