Product Name	lipocalin 1/LCN1
Chinese Name	脂质运载蛋白1抗体
Alias	LCN1; LCN1_HUMAN; Lipocalin 1 (protein migrating faster than albumin, tear prealbumin); Lipocalin 1 like 2; Lipocalin-1; lipocalin 1; PMFA; Tear lipocalin; Tear prealbumin; Tlc; TP antibody VEG protein; VEGP; Von Ebner gland protein.
literatures	Specific References  (1)     |     SL11286R has been referenced in 1 publications. [IF=5.123] Jia, W. et al. Elimination terminal fixed region screening and high-throughput kinetic determination of aptamer for lipocalin-1 by surface plasmon resonance imaging, (2018) Analytica Chimica Acta  SPRi chip ;   PubMed:10.1016/j.aca.2018.09.018
Research Area	Cell biology  Neurobiology  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	17kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human lipocalin 1: 101-176/176
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Lipocalin-1 is a secretory protein that is highly expressed in fluids covering epithelial surfaces such as tears and respiratory secretions. This major lipid-binding protein in tears is also called tear lipocalin (TL) and von Ebner’s gland protein (VEG), as it is also a major secretion of these lingual salivary glands. In addition to lacrimal glands and lingual glands, Lipocalin-1 is secreted by nasal mucosal glands, secretory glands of the tracheobronchial tract, sweat glands, mammary glands, adrenal gland, prostate, thymus, testis and corticotrophs of the pituitary gland. Specifically, Lipocalin-1 functions to stabilize the lipid film of human tear fluid by removing harmful lipids from the human corneal surface and delivering them to the aqueous phase of tears. Lipocalin-1 may also function as a transporter of hydrophobic molecules such as bitter substances on the tongue. Function: Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. Subunit: Homodimer. Binds to LMBR1L which may mediate its endocytosis. Subcellular Location: Secreted. Tissue Specificity: Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate. Similarity: Belongs to the calycin superfamily. Lipocalin family. SWISS: P31025 Gene ID: 3933 Database links: Entrez Gene: 3933 Human Omim: 151675 Human SwissProt: P31025 Human Unigene: 530311 Human

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