Product Name	5HT1A Receptor
Chinese Name	5-羟色胺受体1A抗体
Alias	5HT1A Receptor; HTR1A; 5-HTR1A; 5 HT 1A; 5 HT receptor 1A; 5 HT1A; 5 HT1A receptor; 5 hydroxytryptamine (serotonin) receptor 1A; 5 hydroxytryptamine (serotonin) receptor 1A G protein coupled; 5 hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; 5-hydroxytryptamine receptor 1A; 5HT 1A; 5HT 1A receptor; 5HT receptor 1A; 5HT1a; 5HT1A_HUMAN; ADRB2RL1; ADRBRL1; G 21; G protein coupled receptor; G-21; Gpcr 18; Gpcr18; Guanine nucleotide binding regulatory protein-coupled receptor; PFMCD; Serotonin 1A receptor; Serotonin 5HT1A receptor; Serotonin receptor 1A;
literatures	Specific References  (3)     |     SL1124R has been referenced in 3 publications. [IF=5.62] Zhou, Q. G., et al. "Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert−/− mice."Translational Psychiatry 6.6 (2016): e836.  WB ;  Mouse.   PubMed:27300262 [IF=4.17] Yeh, C-B., et al. "Calcitonin alleviates hyperalgesia in osteoporotic rats by modulating serotonin transporter activity." Osteoporosis International (2016): 1-10.  IHC-F ;  Rat.   PubMed:27260496 [IF=2.72] Lan Yao. et al. Armillaria mellea fermentation liquor ameliorates p-chlorophenylalanine-induced insomnia associated with the modulation of serotonergic system and gut microbiota in rats. 2022 Jan 05  WB,IHC ;  Rat.   PubMed:34984694
Research Area	Tumour  immunology  Neurobiology  Signal transduction  transcriptional regulatory factor  The cell membrane受体  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse, Rat,  (predicted: Dog, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	46kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human 5-HTR1A: 301-400/422 <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the 5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic fevers. [provided by RefSeq, Jun 2012]. Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily. SWISS: P19327 Gene ID: 3350 Database links: Entrez Gene: 487230 Dog Entrez Gene: 3350 Human Entrez Gene: 15550 Mouse Entrez Gene: 24473 Rat Omim: 109760 Human SwissProt: Q6XXX9 Dog SwissProt: Q0EAB6 Horse SwissProt: P08908 Human SwissProt: Q64264 Mouse SwissProt: P19327 Rat Unigene: 247940 Human Unigene: 4716 Mouse Unigene: 44486 Rat
Product Picture	Protein: Brain(Mouse) Lysate at 40 ug Primary: Rabbit Anti- 5HT1A Receptor (SL1124R) at 1:300; Secondary: 800CW Conjugated Goat (polyclonal) Anti-Rabbit IgG(H+L) at 1: 10000; Predicted band size:46 kD Observed band size:56 kD Protein: HepG2 lyates(hu); Primary: Rabbit Anti- 5HT1A Receptor (SL1124R) at 1:300; Secondary: 800CW Conjugated Goat (polyclonal) Anti-Rabbit IgG(H+L) at 1: 10000; Predicted band size:46 kD Observed band size:56 kD Sample: Lane 1: Mouse Brain Lysates Lane 2: Mouse Cerebellum Lysates Lane 3: Mouse Lymph Lysates Lane 4: Rat Brain Lysates Lane 5: Rat Cerebellum Lysates Primary: Anti-5HT1A Receptor (SL1124R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46kDa Observed band size: 46kDa Sample: Jurkat(Human) Cell Lysate at 40 ug Primary: Anti-5HT1A Receptor (SL1124R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kD Observed band size: 46 kD

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