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Product Name DNAH9 Chinese Name 轴丝动力蛋白重链9抗体 Alias Dynein heavy chain; Axonemal beta dynein heavy chain 9; Ciliary dynein heavy chain 9; Ciliary dynein heavy chain; DNAH 9; DNAH17L; DNAH9; DNAH9 variant protein; Dnahc 9; Dnahc9; DNAL 1; DNAL1; DNEL 1; DNEL1; DYH 9; DYH9; Dynein axonemal heavy chain 9; Dynein axonemal heavy polypeptide 17 like; Dynein axonemal heavy polypeptide 9; dynein heavy chain 9, axonemal; HL 20; HL20; KIAA0357; DYH9_HUMAN. Research Area Neurobiology Signal transduction Cell adhesion molecule Cytoskeleton Extracellular matrix Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Horse, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 512kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human DNAH9: 3001-3200/4486 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene expresses at least two transcript variants; additional variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].
Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.
Subunit:
Consists of at least two heavy chains and a number of intermediate and light chains.
Subcellular Location:
Cytoplasmic
Similarity:
Belongs to the dynein heavy chain family.
SWISS:
Q9NYC9
Gene ID:
1770
Database links:Entrez Gene: 1770 Human
Omim: 603330 Human
SwissProt: Q9NYC9 Human
Unigene: 567259 Human
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